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	<title>Pizaazz &#187; Am. Urological Assoc.</title>
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		<title>A Full Head of Hair and No Cancer</title>
		<link>http://www.pizaazz.com/2009/03/13/a-full-head-of-hair-and-no-cancer/</link>
		<comments>http://www.pizaazz.com/2009/03/13/a-full-head-of-hair-and-no-cancer/#comments</comments>
		<pubDate>Fri, 13 Mar 2009 20:06:57 +0000</pubDate>
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				<category><![CDATA[Am. Urological Assoc.]]></category>
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		<category><![CDATA[Pharmaceuticals]]></category>
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		<description><![CDATA[Finasteride cuts the risk of developing prostate cancer by 25%. Yes, that finasteride, the stuff millions of guys use to stop hair loss and pee like a garden hose! The heartening news derives from a final analysis of the Prostate Cancer Prevention trial, a multicenter prospective randomized study of 19,000 men. The survival benefit had actually been [...]]]></description>
			<content:encoded><![CDATA[<!-- Start Shareaholic LikeButtonSetTop --><!-- End Shareaholic LikeButtonSetTop --><p style="text-align: left;">Finasteride cuts the risk of developing prostate cancer by 25%. Yes, that finasteride, the stuff millions of guys use to stop hair loss and pee like a garden hose!</p>
<p style="text-align: left;"><img class="alignleft size-thumbnail wp-image-3775" title="yeababy!" src="http://www.pizaazz.com/wp-content/uploads/2009/03/yeababy-104x150.png" alt="yeababy 104x150 A Full Head of Hair and No Cancer" width="104" height="150" />The heartening news derives from a final analysis of the Prostate Cancer Prevention trial, a multicenter prospective randomized study of 19,000 men.</p>
<p style="text-align: left;">The survival benefit had actually <a href="http://www.washingtonpost.com/wp-dyn/content/article/2009/02/24/AR2009022402934.html" target="_blank">been reported years ago</a>, but at the time it was bundled with the disquieting news that finasteride seemed to cause an uptick in more aggressive forms of prostate cancer.</p>
<p style="text-align: left;">But now it’s official and strange though it may seem, the apparent negative association turned out to be a manifestation of yet another benefit of finsateride&#8211;it facilitates diagnosis of the more virulent cases.</p>
<p style="text-align: left;">&#8220;The goal of developing a chemo-preventive agent that can reduce the risk of prostate cancer has been achieved, and that is…major,&#8221; NIH Barnett Kramer told the Washington Post.</p>
<p style="text-align: left;">In fact based on the newly interpreted findings, Kramer-led guidelines development teams at the American Society of Clinical Oncology and the <a href="http://www.auanet.org/content/guidelines-and-quality-care/clinical-guidelines/main-reports/pcredinh.pdf" target="_blank">American Urological Association </a>co-released statements encouraging men that normally get screened for prostate cancer to speak to their physicians about the matter.</p>
<p style="text-align: left;"><img class="alignright size-thumbnail wp-image-3776" title="waittillyahearthis" src="http://www.pizaazz.com/wp-content/uploads/2009/03/waittillyahearthis-150x112.jpg" alt="waittillyahearthis 150x112 A Full Head of Hair and No Cancer" width="150" height="112" />The guidelines stopped short of recommending that guys should take the drug.</p>
<p style="text-align: left;">A call like that would precipitate ten million  finasteride prescriptions in the blink of an eye.</p>
<p style="text-align: left;">That would be a windfall for Merck but it may not be cost-effective from a societal perspective.</p>
<p style="text-align: left;">Roughly 71 men would have to take the drug for 7 years in order to prevent one case of prostate cancer.  That’s a lot of exposure to potential side effects which, although rare and reversible, include impotence and decreased libido.</p>
<p style="text-align: left;">And since finasteride can run 3 bucks a day, it would cost $500,000 for each “prevented” case of prostate cancer, a high figure since in many cases the disease is rather indolent.</p>
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