Archive for March 18th, 2011

Platelet-Rich Plasma Therapy: Much Ado about Nothing?

March 18th, 2011 | 6 Comments | Source: Commentary

Platelet-rich plasma (PRP) therapy became a hot topic among professional and recreational athletes after some studies suggested it could hasten wound healing and several high-profile athletes reported using it as they rehabbed from various injuries.  But recently, the news hasn’t been quite so good. For those not in the know, let’s do a quick review of the subject.

PRP therapy involves extracting and centrifuging a person’s blood to create a concentrated broth of growth factors and white cells, and then then injecting the stew directly into injured tissue. The growth factors supposedly promote healing.

PRP therapy has been used for numerous conditions including tennis elbow and pulls, sprains and strains of dozens of different muscles, tendons and whatnot.

The treatment became buzzworthy after animal studies showed that it fostered collagen and new blood vessel formation in the tendons of animals that had been surgically injured by scientists.

The buzz grew after reports surfaced that Tiger Woods used PRP therapy to treat a sore knee, NFL player Chris Canty used it for a hamstring injury, and itinerant MLB pitcher Cliff Lee used it for an abdominal strain. After these high-profile athletes claimed to be satisfied with the results, recreational athletes began demanding PRP therapy for themselves, even though it cost $1,000 per shot and isn’t covered by most insurance plans.

Alas, recent scientific studies of PRP therapy should dampen that enthusiasm, at least a bit. It just doesn’t seem to work in humans with overuse injuries and strains, according to these studies.

This month for example, S. de Jonge and colleagues at Erasmus University (Rotterdam) published one-year follow-up data on their placebo-controlled trial of PRP therapy for Achilles tendinopathy. Their original report showed no benefits at 6 months, and the extended follow-up showed the same thing (no benefit). de Jonge’s group concluded there is “no evidence for the use of platelet-rich plasma” therapy in this particular condition. (more…)

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